Disease landscape

Asthma

Moderate restrictions in access to asthma treatment and diagnosis have been identified in the Visegrád (V4) countries as measured in the GAP score. Results vary substantially from country to country and the difference between the highest and the lowest scoring country is about 24 points. The main reason for the relatively unfavorable assessment is limited access to the registered drugs due to the lack of reimbursement or its restrictions and very low share of patients with eosinophilic asthma treated with the newest biological drugs.

Cross-Country

General GAP for Asthma

Poland

60.9

Hungary

53.1

Czechia

77

Slovakia

58.4

Compliance with guidelines

All the most recently authorised drugs in asthma are recommended by clinical guidelines. An average of 63% of them are available in the V4 group. The spread of results for this KPI is large (30 percentage points), indicating a wide variation in access to the latest authorized drugs in these countries.

From registration to reimbursement

Population burden

DALY* - Rate per 100k

*disability adjusted life-years

Target population

patients with eosinophilic asthma

Drug access

Number of patients treated (2021)

Drug access

Population treated* - selected drugs (%)

*percentage of the population of patients with eosinophilic asthma

Main issues

  • The average time to reimbursement for asthma drugs in the V4 countries is 2.0 years. The difference between the shortest and the longest mean time to reimbursement among the countries is 2.5 year.
  • The uptake of newest biological drugs in a target population is low to very low in all states – it is 31% Czechia and it ranges from 4% to 9% in the other V4 countries.
  • Population burden in V4 states is much lower than the European Union average. The only exception is Poland, where the burden of asthma measured in DALYs is in line with the European average. Over the past few years, there has been a trend of a slight increase in DALY values for asthma in the V4 countries.

Project

We measured the gap in innovative drug access and diagnostics in selected therapeutic areas in the Visegrád (V4) countries (Poland, Hungary, Czechia and Slovakia).